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    Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors. Transl Psychiatry. Aberrant cognitive phenotypes and altered hippocampal BDNF expression related to epigenetic modifications in mice lacking the post-synaptic scaffolding protein SHANK1: Implications for autism spectrum disorder.

    Epub May Adult restoration of Shank3 expression rescues selective autistic-like phenotypes.

    Epub Feb Epub Nov Juvenile Shank3b deficient mice present with behavioral phenotype relevant to autism spectrum disorder. Epub Aug Mol Autism. Juvenile Shank3b deficient mice present with behavioral phenotype relevant to autism spectrum disorder.

    Behav Brain Res. Epub Aug Autism Res. Epub Nov Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism.

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    Comprehensive analysis of two Shank3 and the Cacna1c mouse models of autism spectrum disorder. Genes Brain Behav.

    Epub Sep 5. Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors. Transl Psychiatry. Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function.

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